Despite decades of research and billions invested, scientists still cannot stop Parkinson’s disease. For now, says endurance athlete and Parkinson’s advocate Jimmy Choi, the most effective intervention available may be something far less futuristic than many has hoped for: Exercise.
For more than a decade, Anders M. Leines has documented Parkinson’s from the inside. First, he wanted to change how the disease was seen. Ten years later, he returned to the same people, and found a darker story about time and identity.
Parkinson's disease and obstructive sleep apnea are locked in a devastating feedback loop, where each condition exacerbates the other through shared molecular pathways, creating a complex clinical challenge that current, siloed treatments fail to address.
Desulfovibrio is the kind of microbe most people have never heard of, yet it showed up more often and in higher amounts in the sickest among Parkinson’s patients. The temptation is obvious: if a suspicious bacterium tracks disease severity, maybe it helps cause the disease.
An analysis of over 800 brains reveals that the disease bypasses specific motor regions, attacking a newly discovered master network for whole-body coordination.