Oxidative Stress

Aging

The Wrong Suspect in the Cell’s Burn Chamber

For decades, scientists blamed the Krebs cycle and fat-burning machinery for making mitochondria leak toxic peroxide. But under moderate beta-oxidation, the usual suspects are exonerated. The real mystery is not why the cell is burning fuel—it’s what else inside the mitochondrion is making the dangerous exhaust.

Parkinson's Disease

Parkinson's and Sleep Apnea Fuel Each Other

Parkinson's disease and obstructive sleep apnea are locked in a devastating feedback loop, where each condition exacerbates the other through shared molecular pathways, creating a complex clinical challenge that current, siloed treatments fail to address.